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In general, prevention of headaches is considered effective in reducing the frequency of attacks by 50% or more. The FDA approved few drugs used to prevent migraine. The use of most of them was based

Tonabersat is a new drug undergoing And a phase of clinical research as a means for preventing migraine. Tonabersat is a blocker of pervasive cortical depression as the main mechanism of migraine pathogenesis. In a

The first results of preventive measures appear a few weeks or months after the start of treatment. Many patients notice an improvement in condition only when taking medicines in therapeutic doses for 3-4 weeks. To

None of the drugs used to relieve headaches can be effective in every attack. For this reason, for an objective assessment of the effectiveness of treatment, any new drug is evaluated in three bouts of

Although headache treatment is not always effective, patients and doctors have hope of developing new drugs, since chronic headache is at the epicenter of the latest research and development of the pharmaceutical industry. At various

Antiemetic drugs have a good additional effect in the treatment of headaches accompanied by nausea and vomiting. Antiemetics are more effective in combination with analgesics and other drugs to relieve headaches. Monotherapy often provides only

Along with triptans, ergotamine preparations have a good effect in treating headaches that drastically reduce the ability to work. The side effects of ergotamines, due to their vasoconstrictor effect, are more serious than with triptans.

The use of triptans is preferable for patients suffering from moderate to high-intensity headaches, which drastically reduce their ability to work. The choice of triptan depends on some differences in pharmacokinetics and the preferred mode

Pathogenesis of headaches Pathogenesis of tension headache. The pathophysiological changes observed in patients with migraine may also exist in patients with tension headache. In general, tension headache has quality characteristics similar to migraine, differing only

When treating weak and moderate headaches, acetylsalicylic acid and NSAIDs are more effective; acetaminophen® and opioids are less effective. With a combination of 100 mg of caffeine with analgesics, reduction of headaches is observed 1.5