Headache treatment used in adults is also effective in pediatric practice, but there is a certain difference in the selection of doses of drugs. The European Federation of Neuroscience (EVN) has developed recommendations for the effective treatment of migraine in children and adolescents.
The same principles subsequently formed the basis of recommendations.
European Federation of Headache. Effective treatment of migraine in children and adolescents
After the publication of recommendations for the treatment of headaches in children developed by the European Scientific Research Institute, two studies have been published that demonstrated the good efficacy of rizatriptan when taken orally (5 mg for children weighing 20-39 kg and 10 mg for children weighing more than 40 kg) in children and adolescents 6-17 years; as well as zolmitriptan as a nasal spray in adolescents 12-17 years old.
The effectiveness of the relief of headaches (a decrease in intensity from high to weak or up to the disappearance of pain) during treatment with triptans in placebo-controlled studies is shown in the figure.
In all studies, adolescents over the age of 12 years participated, and children from the age of 6 years only in studies of the effectiveness of oral forms of zolmitriptan and rizatriptan.
In the study of the effectiveness of zolmitriptan, taken orally, the children consumed ibuprofen at a dose of 200 mg, and adolescents – 400 mg.